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Interferon Regulatory Factor 6 Promotes Keratinocyte Differentiation in Response to Porphyromonas gingivalis.
Huynh J, Scholz GM, Aw J, Reynolds EC. Huynh J, et al. Infect Immun. 2017 Apr 21;85(5):e00858-16. doi: 10.1128/IAI.00858-16. Print 2017 May. Infect Immun. 2017. PMID: 28289145 Free PMC article.
We recently demonstrated that the expression of the interferon regulatory factor 6 (IRF6) transcription factor in oral keratinocytes was stimulated by the periodontal pathogen Porphyromonas gingivalis Here, we have established that IRF6 promotes the differentiation of oral kerati …
We recently demonstrated that the expression of the interferon regulatory factor 6 (IRF6) transcription factor in oral keratinocytes was sti …
Keratin 13 gene is epigenetically suppressed during transforming growth factor-β1-induced epithelial-mesenchymal transition in a human keratinocyte cell line.
Hatta M, Miyake Y, Uchida K, Yamazaki J. Hatta M, et al. Biochem Biophys Res Commun. 2018 Feb 5;496(2):381-386. doi: 10.1016/j.bbrc.2018.01.047. Epub 2018 Jan 8. Biochem Biophys Res Commun. 2018. PMID: 29326042
Quantitative RT-PCR analysis revealed that TGF-beta1 increased the mRNA levels of EMT transcription factors (SNAI2, TWIST1, and ZEB1) and mesenchymal markers (CDH2, VIM, and FN1), while it decreased the transcripts of epithelial phenotypic genes (CLDN1, OCLN, KRT5, KRT15, KRT1 …
Quantitative RT-PCR analysis revealed that TGF-beta1 increased the mRNA levels of EMT transcription factors (SNAI2, TWIST1, and ZEB1) and me …